[et_pb_section fb_built=”1″ admin_label=”Cardiosmile” _builder_version=”4.4.2″ background_color=”#ffffff” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” locked=”off” collapsed=”off”][et_pb_row _builder_version=”4.5.8″ module_alignment=”center” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false”][et_pb_column type=”4_4″ _builder_version=”4.5.8″][et_pb_text _builder_version=”4.4.2″ text_text_color=”#3575ab” header_font=”|600|||||||” header_text_color=”#3575ab” custom_margin=”||10px||false|false”]
Cardiosmile Plant Sterols
[/et_pb_text][et_pb_divider color=”#3575ab” _builder_version=”4.4.8″ custom_margin=”||5px||false|false”][/et_pb_divider][/et_pb_column][/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.4.8″ module_alignment=”center”][et_pb_column type=”1_2″ _builder_version=”4.4.2″][et_pb_text _builder_version=”4.4.2″ text_text_color=”#00a44b” header_text_color=”#000000″ header_2_text_color=”#3575ab” custom_margin=”||10px||false|false”]
What are plant sterols?
[/et_pb_text][et_pb_divider color=”#3575ab” _builder_version=”4.4.2″ custom_margin=”||5px||false|false”][/et_pb_divider][et_pb_text _builder_version=”4.5.1″ text_text_color=”#444444″ text_font_size=”16px” header_text_color=”#3575ab”]
They are natural substances present in foods such as legumes, fruits, and vegetables. You could say that they are like the “cholesterol” of vegetables, because their molecular structure is very similar to that of cholesterol, and just like it, they perform a structural function in the organisms that contain them.
What makes plant sterols so beneficial is that their components block the absorption of both endogenous cholesterol (produced by your liver) and exogenous cholesterol (coming from animal source foods) in your intestine. That is how they help control cholesterol levels in your body and contribute to the prevention of cardiovascular disease and other conditions caused by metabolic deviations.
Various meta-analyses report that a daily intake of 2 grams of plant sterols lowers cholesterol by 10% to 15% (Demonty, 2009; AbuMweis, 2008; Ras, 2013). Suggested cholesterol-lowering mechanisms are (De Smet, 2012): inhibiting cholesterol absorption in the enterocyte, inhibiting its re-esterification and thus avoiding its incorporation into lipoproteins and expelling unesterified cholesterol back to the intestinal lumen.
[/et_pb_text][/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.4.2″][et_pb_image src=”https://www.nutrartis.com/wp-content/uploads/2020/06/Plant-sterols.png” alt=”Plant sterols” title_text=”Plant sterols” _builder_version=”4.4.8″ transform_scale=”120%|120%” transform_translate=”0px|33px” module_alignment=”center” hover_enabled=”0″][/et_pb_image][/et_pb_column][/et_pb_row][/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” admin_label=”Pine Sterols” _builder_version=”4.4.8″ background_image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Pine-Sterols-scaled.jpg” parallax=”on” parallax_method=”off” hover_transition_speed_curve=”ease-in-out” motion_trigger_start=”top” background_last_edited=”off|phone” parallax_method_phone=”off” locked=”off” collapsed=”on” background__hover_enabled=”off|hover”][et_pb_fullwidth_header title=” ” subhead=” ” _builder_version=”4.4.8″ background_color=”rgba(255,255,255,0)”][/et_pb_fullwidth_header][/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Nano dispersion” _builder_version=”4.4.2″ background_color=”#ffffff” custom_padding=”0px||0px||false|false” locked=”off” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.4.8″ background_enable_color=”off” module_alignment=”center” custom_padding=”0px||0px||false|false”][et_pb_column type=”1_2″ _builder_version=”4.4.2″][et_pb_text _builder_version=”4.4.2″ text_text_color=”#00a44b” header_text_color=”#3575ab” header_2_text_color=”#3575ab” custom_margin=”25px||10px||false|false” locked=”off”]
Cardiosmile, a Novel Nano-dispersion
[/et_pb_text][et_pb_divider color=”#3575ab” _builder_version=”4.4.2″ custom_margin=”||5px||false|false” locked=”off”][/et_pb_divider][et_pb_text _builder_version=”4.4.8″ text_text_color=”#444444″ text_font_size=”16px” header_text_color=”#3575ab”]
Due to the chemical structure and the low solubility of plant sterols, they must be formulated correctly in order to obtain optimum health benefits. Traditionally, this has been done by esterification with fatty acids of vegetable origin which allow higher solubility in fats, and they are later incorporated into margarine, milk, or yogurt.
After several years of research, NUTRARTIS created CARDIOSMILE, the first product to incorporate 2 grams of fat-free plant sterols. This is done by reducing plant sterol particles to a submicron size (400 nm average), which enable particles to remain dispersed in water in a stable manner with minimum use of surfactants.
[/et_pb_text][et_pb_image src=”https://www.nutrartis.com/wp-content/uploads/2020/06/Plant-Sterols-nanodispersion-1.png” alt=”Plant Sterols nanodispersion” title_text=”Plant Sterols nanodispersion” align=”right” _builder_version=”4.4.8″ module_alignment=”left” custom_margin=”||||false|false” custom_padding=”||||false|false”][/et_pb_image][/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.4.2″][et_pb_image src=”https://www.nutrartis.com/wp-content/uploads/2020/06/Nanodispersion-under-microscope-e1600971596820.png” alt=”Nanodispersion under microscope” title_text=”Nanodispersion under microscope” show_bottom_space=”off” _builder_version=”4.4.2″][/et_pb_image][/et_pb_column][/et_pb_row][/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” admin_label=”Pine Sterols” _builder_version=”4.4.8″ background_image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Pine-Sterols-scaled.jpg” parallax=”on” parallax_method=”off” hover_transition_speed_curve=”ease-in-out” motion_trigger_start=”top” background_last_edited=”off|phone” parallax_method_phone=”off” locked=”off” collapsed=”on” background__hover_enabled=”off|hover”][et_pb_fullwidth_header title=” ” subhead=” ” _builder_version=”4.4.8″ background_color=”rgba(255,255,255,0)”][/et_pb_fullwidth_header][/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Cardiosmile” _builder_version=”4.4.2″ background_color=”#ffffff” custom_padding=”0px||0px||false|false” locked=”off” collapsed=”off”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.5.8″ module_alignment=”center” custom_padding=”||||false|false”][et_pb_column type=”1_2″ _builder_version=”4.4.2″][et_pb_text _builder_version=”4.4.2″ text_text_color=”#444444″ text_font_size=”16px” header_text_color=”#3575ab” custom_margin=”||||false|false”]
With this novel solution not only it is possible to quickly mix CARDIOSMILE into any type of food, but most importantly, its clinical effectiveness in lowering cholesterol levels can be guaranteed. Additionally, our product:
[/et_pb_text][et_pb_blurb image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Recurso-1@2x.png” icon_placement=”left” image_max_width=”75%” content_max_width=”1100px” _builder_version=”4.4.8″ header_text_align=”left” header_text_color=”#ffffff” body_font_size=”16px” custom_margin=”||12px||false|false” custom_padding=”0px||||false|false” locked=”off”]
It is cholesterol free.
[/et_pb_blurb][et_pb_blurb image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Recurso-1@2x.png” icon_placement=”left” image_max_width=”75%” content_max_width=”1100px” _builder_version=”4.4.8″ header_text_align=”left” header_text_color=”#ffffff” body_font_size=”16px” custom_margin=”||12px||false|false” custom_padding=”0px||||false|false” locked=”off”]
It is calorie free.
[/et_pb_blurb][et_pb_blurb image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Recurso-1@2x.png” icon_placement=”left” image_max_width=”75%” content_max_width=”1100px” _builder_version=”4.4.8″ header_text_align=”left” header_text_color=”#ffffff” body_font_size=”16px” custom_margin=”||12px||false|false” custom_padding=”0px||||false|false” locked=”off”]
It has no trans or saturated fats.
[/et_pb_blurb][et_pb_blurb image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Recurso-1@2x.png” icon_placement=”left” image_max_width=”75%” content_max_width=”1100px” _builder_version=”4.4.8″ header_text_align=”left” header_text_color=”#ffffff” body_font_size=”16px” custom_margin=”||12px||false|false” custom_padding=”0px||||false|false” locked=”off”]
It does not need refrigeration.
[/et_pb_blurb][et_pb_blurb image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Recurso-1@2x.png” icon_placement=”left” image_max_width=”75%” content_max_width=”1100px” _builder_version=”4.4.8″ header_text_align=”left” header_text_color=”#ffffff” body_font_size=”16px” custom_margin=”||12px||false|false” custom_padding=”0px||||false|false” locked=”off”]
It can be mixed into any food base without changing its taste or smell.
[/et_pb_blurb][et_pb_text _builder_version=”4.4.2″ text_text_color=”#444444″ text_font_size=”16px” header_text_color=”#3575ab” custom_margin=”||0px||false|false” custom_padding=”1px|||||”]
A clinical study that compared CARDIOSMILE to traditional plant sterol esters showed an effective reduction in LDL cholesterol after one week, which proves the clinical effectiveness hypothesis. And surprisingly, unlike other plant sterols CARDIOSMILE produced a significant decrease in patients’ triglyceride levels over the same period of intervention of one month*.
[/et_pb_text][et_pb_text _builder_version=”4.4.8″ text_text_color=”#444444″ text_font_size=”12px” header_text_color=”#3575ab”]
(*) Amir Shaghaghi, J.Funct.Food 2014, 280-289
[/et_pb_text][/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.4.2″][et_pb_image src=”https://www.nutrartis.com/wp-content/uploads/2020/09/Cardiosmile-caja-30-1.png” alt=”Cardiosmile package” title_text=”Cardiosmile package” _builder_version=”4.4.2″ transform_scale=”120%|120%” module_alignment=”center” custom_margin=”30px||||false|false” hover_enabled=”0″][/et_pb_image][et_pb_image src=”https://www.nutrartis.com/wp-content/uploads/2020/06/Clinically-Tested-e1592441078888.png” alt=”Clinically Tested” title_text=”Clinically Tested” show_bottom_space=”off” align=”center” _builder_version=”4.5.8″ max_width=”30%” module_alignment=”center” custom_margin=”20px||20px||false|false” custom_padding=”10px||10px||false|false”][/et_pb_image][/et_pb_column][/et_pb_row][/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” admin_label=”Pine Sterols” _builder_version=”4.4.8″ background_image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Pine-Sterols-scaled.jpg” parallax=”on” parallax_method=”off” hover_transition_speed_curve=”ease-in-out” motion_trigger_start=”top” background_last_edited=”off|phone” parallax_method_phone=”off” locked=”off” collapsed=”on” background__hover_enabled=”off|hover”][et_pb_fullwidth_header title=” ” subhead=” ” _builder_version=”4.4.8″ background_color=”rgba(255,255,255,0)”][/et_pb_fullwidth_header][/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Manufacturing” _builder_version=”4.4.2″ background_color=”#ffffff” custom_padding=”0px||0px||false|false” locked=”off” collapsed=”on”][et_pb_row _builder_version=”4.4.2″ background_enable_color=”off” module_alignment=”center” custom_padding=”0px||||false|false”][et_pb_column type=”4_4″ _builder_version=”4.4.2″][et_pb_text _builder_version=”4.4.2″ text_text_color=”#00a44b” header_text_color=”#3575ab” header_2_text_color=”#3575ab” custom_margin=”25px||10px||false|false” locked=”off”]
Manufacturing
[/et_pb_text][et_pb_divider color=”#3575ab” _builder_version=”4.4.2″ custom_margin=”||5px||false|false” locked=”off”][/et_pb_divider][et_pb_text _builder_version=”4.4.2″ text_text_color=”#444444″ text_font_size=”16px” header_text_color=”#3575ab”]
CARDIOSMILE‘s manufacturing process was developed over the course of ten years. Its unique patented process combines a set of never-seen-before process conditions, which is why our plant was designed and built in-house, working with industry partners to comply with the most stringent GMP guidelines. The process itself consists of very few unitary steps, chiefly creating a lipid-in-water emulsion, to then crystallize the lipid particles to yield a stable sub-micron dispersion with a high sterol content. Our experts jointly accumulate several decades of experience, making our process virtually irreplicable.
Currently, our one-of-a-kind plant located in the heart of Chile has the capability to manufacture 1.000.000 Cardiosmile units per year, although our vision includes plans to create capacity in other countries as demand requires.
[/et_pb_text][et_pb_image src=”https://www.nutrartis.com/wp-content/uploads/2020/09/Planta-Nutrartis-e1600962789324.jpg” admin_label=”Foto planta” _builder_version=”4.4.2″ max_width=”80%” max_width_tablet=”100%” max_width_phone=”100%” max_width_last_edited=”on|desktop” module_alignment=”center”][/et_pb_image][/et_pb_column][/et_pb_row][/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” admin_label=”Pine Sterols” _builder_version=”4.4.8″ background_image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Pine-Sterols-scaled.jpg” parallax=”on” parallax_method=”off” hover_transition_speed_curve=”ease-in-out” motion_trigger_start=”top” background_last_edited=”off|phone” parallax_method_phone=”off” locked=”off” collapsed=”on” background__hover_enabled=”off|hover”][et_pb_fullwidth_header title=” ” subhead=” ” _builder_version=”4.4.8″ background_color=”rgba(255,255,255,0)”][/et_pb_fullwidth_header][/et_pb_section][et_pb_section fb_built=”1″ admin_label=”QUALITY” _builder_version=”4.4.8″ custom_padding=”0px||0px||false|false” locked=”off” collapsed=”on”][et_pb_row _builder_version=”4.4.2″ module_alignment=”center” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false”][et_pb_column type=”4_4″ _builder_version=”4.4.2″][et_pb_text _builder_version=”4.4.2″ text_text_color=”#00a44b” header_text_color=”#3575ab” header_2_text_color=”#3575ab” custom_margin=”||10px||false|false” locked=”off”]
Quality
[/et_pb_text][et_pb_divider color=”#3575ab” _builder_version=”4.4.2″ custom_margin=”||5px||false|false”][/et_pb_divider][et_pb_text _builder_version=”4.4.2″ text_text_color=”#444444″ text_font_size=”16px” header_text_color=”#3575ab” custom_margin=”||0px||false|false”]
In order to certify CARDIOSMILE’s quality and its compliance with regulations from different countries. NUTRARTIS has ensured that our product is certified as follows:
[/et_pb_text][/et_pb_column][/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.4.2″ custom_padding=”||0px||false|false”][et_pb_column type=”1_4″ _builder_version=”4.4.8″][et_pb_blurb title=”KOSHER PRODUCT” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9hdHRhY2htZW50Iiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjM5NCJ9fQ==@” url_new_window=”on” image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Kosher.png” alt=”Kosher” admin_label=”Kosher Product” _builder_version=”4.5.1″ _dynamic_attributes=”url” header_text_align=”center”][/et_pb_blurb][/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.4.8″][et_pb_blurb title=”HALAL” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9hdHRhY2htZW50Iiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjM5MyJ9fQ==@” url_new_window=”on” image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Halal.png” alt=”Halal” admin_label=”HALAL” _builder_version=”4.5.1″ _dynamic_attributes=”url” header_text_align=”center”][/et_pb_blurb][/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.4.8″][et_pb_blurb title=”VEGAN” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9hdHRhY2htZW50Iiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjM5NSJ9fQ==@” url_new_window=”on” image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Vegan.png” alt=”Vegan” admin_label=”Vegan” _builder_version=”4.5.1″ _dynamic_attributes=”url” header_text_align=”center”][/et_pb_blurb][/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.4.8″][et_pb_blurb title=”HACCP” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9hdHRhY2htZW50Iiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjM5NiJ9fQ==@” url_new_window=”on” image=”https://www.nutrartis.com/wp-content/uploads/2020/06/HACCP.png” alt=”HACCP” admin_label=”HACCP” _builder_version=”4.5.1″ _dynamic_attributes=”url” header_text_align=”center”][/et_pb_blurb][/et_pb_column][/et_pb_row][et_pb_row _builder_version=”4.4.2″ module_alignment=”center” custom_padding=”||0px||false|false”][et_pb_column type=”4_4″ _builder_version=”4.4.2″][et_pb_text _builder_version=”4.5.8″ text_text_color=”#444444″ text_font_size=”16px” header_text_color=”#3575ab” custom_margin=”||0px||false|false”]
Our operations follow the principles of Good Manufacturing Practices according to United States’ NSF (US 21 CFR 110).
[/et_pb_text][/et_pb_column][/et_pb_row][/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” admin_label=”Pine Sterols” _builder_version=”4.4.8″ background_image=”https://www.nutrartis.com/wp-content/uploads/2020/06/Pine-Sterols-scaled.jpg” parallax=”on” parallax_method=”off” hover_transition_speed_curve=”ease-in-out” motion_trigger_start=”top” background_last_edited=”off|phone” parallax_method_phone=”off” locked=”off” collapsed=”on” background__hover_enabled=”off|hover”][et_pb_fullwidth_header title=” ” subhead=” ” _builder_version=”4.4.8″ background_color=”rgba(255,255,255,0)”][/et_pb_fullwidth_header][/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Want to know more?? Contact us” _builder_version=”4.4.2″ background_color=”rgba(53,117,171,0.19)” custom_padding=”0px||0px||false|false” global_module=”955″ saved_tabs=”all” locked=”off” collapsed=”off”][et_pb_row _builder_version=”4.4.2″ custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false”][et_pb_column type=”4_4″ _builder_version=”4.4.2″][et_pb_cta title=”Do you want to know more?” button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIwOCJ9fQ==@” button_text=”Ask us here…” _builder_version=”4.4.2″ _dynamic_attributes=”button_url,link_option_url” header_text_color=”#3575ab” background_color=”rgba(0,0,0,0)” custom_button=”on” button_text_color=”#ffffff” button_bg_color=”#3575ab” button_icon=”%%20%%” background_layout=”light” link_option_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIwOCJ9fQ==@”]
Do you want more information about CARDIOSMILE product technology & applications, clinical studies (research agreements or support in the formulation or development of a clinical study of interest), or how to be our business partner in your country to co-create the new health paradigm? Then send us a message and we’ll contact you as soon as possible.
[/et_pb_cta][/et_pb_column][/et_pb_row][/et_pb_section]