CLINICAL TRIALS

UNIVERSITY OF MANITOBA, CANADÁ, 2014

This study proved the efficacy of CARDIOSMILE, a water-dispersible formulation of free phytosterols versus traditional phytosterol esters, thus supporting the claim that there may be additional advantages in a highly dispersible form of phytosterols in terms of controlling lipid levels. Access the full paper here: Water dispersible plant sterol formulation shows improved effect on lipid profile compared to plant sterol esters (https://www.sciencedirect.com/science/article/abs/pii/S1756464613002454)

UNIVERSITY OF LOS ANDES, CHILE, 2020

This study determined the possible link between a reduction in waist size and triglycerides levels, with an increase in intestinal transit. Lipid and glucose metabolism in patients with metabolic syndrome, differ from healthy people; in particular, lower cholesterol absorption and smaller LDL size reflect the effect of phytosterols on VLDL, and not LDL. Access the full paper here: Effects of Daily Consumption of an Aqueous Dispersion of Free-Phytosterols Nanoparticles on Individuals with Metabolic Syndrome (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468816/)

CECIM, CHILE, 2023

This study showed the effect of a sub-micron dispersion in reducing liver fat and having positive effect on other NASH-pertinent molecular targets (plasma triglycerides, VLDL-P, HDL-P, etc.). It was effective over a range of baseline liver fat levels.
Access the full paper here: Efficacy of Submicron Dispersible Free Phytosterols on Non-Alcoholic Fatty Liver Disease (https://www.mdpi.com/2077-0383/12/3/979)

UNIVERSITY OF TORONTO, CANADA, to be published

The purpose of this study is to determine whether a dietary portfolio of cholesterol-lowering foods (viscous fibers, soy protein, plant sterols and nuts) further enhanced by increased levels of monounsaturated fatty acids (MUFA) and low glycemic index foods, together with a structured exercise program, reduce the progression of carotid and coronary atheromatous lesions, low-density lipoprotein cholesterol (LDL-C), and blood pressure, while reducing the number of individuals requiring statins.

ONGOING STUDIES

Part of our philosophy is to continue working on innovation, development, and scientific evidence. This is why we are permanently conducting new studies to prove the effectiveness and new applications of phytosterol sub-micron dispersions.